HomeExecutive Compensation

Understanding Compensation Dynamics at iTeos Therapeutics


Posted: 05/14/2025 03:39 am


iTeos Therapeutics, Inc. (NASDAQ: ITOS), a pioneering entity in the realm of immuno-oncology therapeutics, displays an intriguing compensation trajectory reflective of its pivotal role in the industry. Recent developments in the company's financial outlook and executive compensations provide valuable insights into its strategic incentives and market positioning.

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In 2024, Dr. David Feltquate, M.D., Ph.D., took center stage as one of the notable figures at iTeos with a total compensation package of approximately $5.06 million. This package includes a base salary of $214,271, supplemented significantly by an option award valued at $4.19 million, indicating the firm's emphasis on long-term, stock-based incentives to align executive performance with shareholder interests^1.

Earlier in 2023, Matthew Call, serving as Chief Operating Officer, was compensated a total of around $2.80 million. A notable portion of Mr. Call's compensation was his option award of $1.66 million, underscoring a consistent pattern within iTeos to motivate its leadership through equity incentives, although this was less than his 2021 compensation of $4.22 million^2. The variation reflects changes in company priorities and potentially, the market conditions impacting equity valuations.

Going back further, the 2021 compensation of iTeos' Chief Executive Officer, Michel Detheux, Ph.D., stood at approximately $5.60 million, with substantial option awards being a common compensation feature, reflecting the high-risk, high-reward nature of biopharmaceutical ventures^3. Dr. Detheux's 2019 compensation, for instance, was significantly lower at $1.58 million, hinting at dynamic growth phases within the company and adjustments in compensation strategy relative to industry benchmarks^4.

iTeos' market performance provides a context to these compensation figures. Recent headlines have showcased mixed developments—with the GALAXIES Lung-201 clinical study not meeting its targeted clinical objectives^5, potentially affecting investor sentiment, which might be reflected in executive incentive structures. Despite a notable rise in the stock price driven by positive earnings revisions and analyst optimism^6, the company's shares closed recently at $7.85, still significantly below their 52-week high of $18.70^7. This volatility highlights the challenges and opportunities iTeos faces in a competitive biopharmaceutical market.

In conclusion, iTeos' compensation strategies underscore a concerted effort to link leadership incentives closely with long-term corporate achievements. As the firm continues to navigate the complexities of drug development and market reception, these compensation figures serve as a testament to its strategic alignment towards fostering innovation while adapting to external market dynamics.

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1. SEC filing, 2024: [David Feltquate Compensation](https://www.sec.gov/Archives/edgar/data/1808865/000095017025057666/0000950170-25-057666-index.htm)
2. SEC filing, 2023: [Matthew Call Compensation](https://www.sec.gov/Archives/edgar/data/1808865/000095017024047915/0000950170-24-047915-index.htm)
3. SEC filing, 2021: [Michel Detheux Compensation](https://www.sec.gov/Archives/edgar/data/1808865/000095017023014989/0000950170-23-014989-index.htm)
4. SEC filing, 2019: [Michel Detheux Compensation](https://www.sec.gov/Archives/edgar/data/1808865/000119312521151713/0001193125-21-151713-index.htm)
5. GlobeNewswire, 2025: [Study Results](https://www.globenewswire.com/news-release/2025/05/13/3080020/0/en/iTeos-Reports-Topline-Interim-Results-from-GALAXIES-Lung-201-Study-of-Belrestotug-Dostarlimab-in-First-Line-PD-L1-High-Non-Small-Cell-Lung-Cancer-Patients.html)
6. Zacks, 2025: [Analyst Report](https://www.zacks.com/stock/news/2461262/wall-street-analysts-see-a-211-07-upside-in-iteos-therapeutics-itos-can-the-stock-really-move-this-high%3Fcid%3DCS-STOCKNEWSAPI-FT-tale_of_the_tape%7Cconsensus_price_target-2461262)
7. Market data, 2025: [iTeos Stock Snapshot](https://www.nasdaq.com/market-activity/stocks/itos)


 

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