HomeExecutive Compensation

In the competitive field of pharmaceutical preparations, Upstream Bio, Inc


Posted: 05/08/2025 03:40 am


A closer look at Upstream Bio's compensation structure reveals the striking recompense of its leadership team. In 2024, Dr. E. Rand Sutherland, a key figure in UPB's strategic direction, secured a comprehensive compensation package totaling $9,108,953. This package is composed of a $407,955 salary, an impressive $8,375,648 in option awards, and $315,000 from the company's incentive plan. Although no traditional bonus or stock awards were reported, this compensation underlines UPB's confidence in its top executives to drive the company through its experimental clinical stages.[^2]

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The stock market has responded positively to recent developments at UPB, reflecting investor optimism. UPB's share price currently stands at $8.58, showing a 4.5% rise, with a day high of $9.165, against a year-high contrast of $29.46. The company's market capitalization is approximately $460.65 million, indicating a robust investor base and significant market interest in UPB's future growth trajectory.[^3]

News from UPB continues to highlight the company's dynamic progress. In early May 2025, Upstream Bio reported its financial results for the first quarter, including accelerated guidance across all clinical programs. Notably, early data from the company's Phase 2 clinical trials for verkitug in treating chronic rhinosinusitis with nasal polyps and severe asthma are eagerly anticipated in late 2025 and early 2026, respectively. Such progress could bolster UPB's standing as a pivotal player in addressing severe respiratory disorders.[^4]

With its recent addition to the Russell 2000 Index in December 2024, Upstream Bio's profile has risen among small-cap investors, marking a significant milestone in its post-IPO journey. This inclusion reflects the company's ascending prominence and the strategic importance of its research and development efforts in the broader pharmaceutical industry.[^5]

[^1]: Seeking Alpha, "Upstream Bio: Treating Respiratory Disorders With TSLP Targeting Differentiation," December 16, 2024.
[^2]: U.S. Securities and Exchange Commission, "Executive Compensation Package for E. Rand Sutherland, M.D.," 2024.
[^3]: NASDAQ Stock Information for Upstream Bio, Inc.
[^4]: GlobeNewswire, "Upstream Bio Reports First Quarter 2025 Financial Results and Accelerates Guidance on All Clinical Programs," May 06, 2025.
[^5]: GlobeNewswire, "Upstream Bio Announces Addition to Russell 2000® Index," December 16, 2024.


 

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